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KMID : 0367420040470101106
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Journal of Korean Pediatric Society
2004 Volume.47 No. 10 p.1106 ~ p.1109
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A Case of Fulminant Hepatitis from Hepatitis A in a Child.
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Kim Young-Min
Kim Jae-Sun
Bae Sun-Hwan
Kim Dong-Hoon
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Abstract
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Fulminant hepatitis from hepatitis A in children is rare and has a low survival rate. We report a case of fulminant hepatitis from hepatitis A in a 12-year-old girl. The patient was admitted because of a three day history of fever, epigastric pain and vomiting. On her second hospital day, she had insomnia, anxiety, dysthesia, continuous fever, vomiting and nausea. In laboratory findings, decreased white blood cell and platelet count, markedly elevated serum aminotransferase levels, elevated serum bilirubin levels, prolonged prothrombin time and partial thromboplastin time were seen. Factor VIII appeared normal range. The histopathologic findings were necrosis in hepatic lobules, periportal necrosis, portal lymphocytic infiltration and fibrous portal expansion. We treated the patient with supportive care. After treatment, clinical manifestations and laboratory findings were improved. (Korean J Pediatr 2004;47:1106-1109)
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KEYWORD
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Hepatitis A, Fulminant hepatitis, Child
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